Publications and Patents

Intellectual Property

OrPro files patents in the US and internationally to protect its innovations. Patentable and non-patentable IP (know-how, trade secrets) is protected via strict confidentiality agreements, third-party contracts, and employee/consultant IP assignments. OrPro’s patent attorneys are Sheridan Ross, LLP (Denver, CO) and Wilson Sonsini Goodrich & Rosati (San Diego, CA), and its corporate and legal counsel is Latham and Watkins, LLP (San Diego, CA).  Issued US patents in-licensed exclusively to OrPro or invented in-house:


Heifetz, P.B., Rancourt, R.C., and Nichols, D. (2014) “A novel inhaled mucus normalizing therapy for cystic fibrosis”, Pediatric Pulmonology, 49(S38), 307

Heifetz, P.B., Moskowitz, H, Nichols, D and Rancourt, R.C. (2015) “pH dependency of mucolytic agents: the case for protein-drug mucus normalization”, Pediatric Pulmonology, 50(S41), 235

Falk Libby, E., Fortinberry, H., Birket, S., Moskowitz, H., Hill, D.B., Tearney, G.J., Rowe, S.M., and Heifetz, P.B. (2016) “Theradux™, a novel biologic derived from optimized thioredoxin-1, improves mucociliary transport in situ”, Pediatric Pulmonology, 51(S45), 292-3

Chand, R., P.J. Kuehl, P.B. Heifetz, H. Moskowitz, and J.D. McDonald: “Non-clinical inhalation delivery of a biological”. In: Proceedings of Respiratory Drug Delivery 2016, Vol. 2 (R. N. Dalby, P. R. Byron, J. Peart, J. D. Suman, S. J. Farr and P. M. Young, eds.), pp. 415-418, Virginia Commonwealth University Richmond, VA, 2016.